منابع مشابه
Proteases in blood clotting.
The serine proteases, cofactors and cell-receptor molecules that comprise the haemostatic mechanism are highly conserved modular proteins that have evolved to participate in biochemical reactions in blood coagulation, anticoagulation and fibrinolysis. Blood coagulation is initiated by exposure of tissue factor, which forms a complex with factor VIIa and factor X, which results in the generation...
متن کاملBlood Clotting Enzymology
Dr. Nelson is an endoscopist, and his technique involves introducing a small Geiger counter through an esophagoscope (or sigmoidoscope) and recording counting rates over the surface of the organ being examined in a patient who has received 500 uc. Of p32 the day before the exam. A positive result is obtained when a clear increase in counting rate is observed at some area as the counter is moved...
متن کاملA circulation inhibitor (anti-AcG) specific for the labile factor-V of the blood-clotting mechanism.
By JOHN H. FERGUSON, CHARLES L. JOHNSTON, JR. AND DORIS A. HOWELL T HE RECENT hematobogic literature contains an increasing number of reports of hemorrhagic diathesis related to the presence of some acquired type of circulating inhibitor interfering with the blood-clotting mechanism. Stefanini and Dameshek,29 on pp. 205-213 of their book, reviewed many of the alleged types and associations with...
متن کاملA Mathematical Model for Blood Clotting
Many biological phenomena are characterized by extensive fluid mechanical and chemical reactionary systems. As such, it is necessary to understand the manner in which these processes develop and the role that they play in a given system. Vascular blood flow is characterized by convective, diffusive, and reactive processes. Specifically, blood clot formation involves platelet convection within t...
متن کاملBlood clotting in minimally altered whole blood.
The sequences of events regulating thrombin generation during tissue factor-initiated clotting in whole blood at 37 degrees C in which the contact pathway was suppressed with corn trypsin inhibitor are studied using quantitative Western blotting of factor V, prothrombin, platelet factor 4, antithrombin III, and fibrinogen. In addition, fibrinopeptide A (FPA), thrombin-antithrombin III (TAT) com...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1948
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)57358-0